MvfR Controls Tolerance to Polymyxin B by Regulating rfaD in Pseudomonas aeruginosa

MvfR Controls Tolerance to Polymyxin B by Regulating rfaD in Pseudomonas aeruginosa

ABSTRACT Polymyxins are currently the last-resort antibiotics for the treatment of multidrug-resistant Gram-negative bacterial infections. To expand the understanding of the intrinsic resistance mechanism against polymyxins, a laboratory strain of Pseudomonas aeruginosa PAO1 was subjected to serial...

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Bibliographic Details
Main Authors: Fan Yang, Yuchen Zhou, Yuxi Bai, Xiaolei Pan, Un-Hwan Ha, Zhihui Cheng, Weihui Wu, Yongxin Jin, Fang Bai
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
mvfR
polymyxin resistance
LPS
Pseudomonas aeruginosa
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00426-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.00426-23

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