Cooperative lipolytic control of neuronal triacylglycerol by spastic paraplegia-associated enzyme DDHD2 and ATGL

Cooperative lipolytic control of neuronal triacylglycerol by spastic paraplegia-associated enzyme DDHD2 and ATGL

Intracellular lipolysis—the enzymatic breakdown of lipid droplet-associated triacylglycerol (TAG)—depends on the cooperative action of several hydrolytic enzymes and regulatory proteins, together designated as lipolysome. Adipose triglyceride lipase (ATGL) acts as a major cellular TAG hydrolase and...

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Bibliographic Details
Main Authors: Peter Hofer, Gernot F. Grabner, Mario König, Hao Xie, Dominik Bulfon, Anton E. Ludwig, Heimo Wolinski, Robert Zimmermann, Rudolf Zechner, Christoph Heier
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Lipid Research
Subjects:
Lipolysis and fatty acid metabolism
brain lipids
enzymology
lipase
triacylglycerol
lipid droplets
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752300130X

Internet

http://www.sciencedirect.com/science/article/pii/S002222752300130X

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