Retrotransposon gag-like 1 (RTL1) and the molecular evolution of self-targeting imprinted microRNAs

Abstract Background Transcription of the antisense strand of RTL1 produces a sense mRNA that is targeted for degradation by antisense microRNAs transcribed from the sense strand. Translation of the mRNA produces a retrotransposon-derived protein that is implicated in placental development. The sense...

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Bibliographic Details
Main Authors: Avantika Mainieri, David Haig
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Biology Direct
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13062-019-0250-0