Paternal methamphetamine exposure induces higher sensitivity to methamphetamine in male offspring through driving ADRB1 on CaMKII-positive neurons in mPFC

Paternal methamphetamine exposure induces higher sensitivity to methamphetamine in male offspring through driving ADRB1 on CaMKII-positive neurons in mPFC

Abstract Paternal abuse of drugs, such as methamphetamine (METH), elevates the risk of developing addiction in subsequent generations, however, its underlying molecular mechanism remains poorly understood. Male adult mice (F0) were exposed to METH for 30 days, followed by mating with naïve female mi...

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Bibliographic Details
Main Authors: Yanyan Zheng, Dekang Liu, Hao Guo, Wenwen Chen, Zhaoyu Liu, Zhaosu Li, Tao Hu, Yuanyuan Zhang, Xiang Li, Ziheng Zhao, Qinglong Cai, Feifei Ge, Yu Fan, Xiaowei Guan
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02624-x

Internet

https://doi.org/10.1038/s41398-023-02624-x

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