Aspartate and Acetate Fuel Gastrointestinal Stromal Tumors Beyond the Warburg Effect

Background:. Metabolic reprogramming is closely linked to the tumorigenesis and drug resistance of gastrointestinal stromal tumors (GISTs). Mapping the metabolic orbit of GISTs is a prerequisite if intervention against the metabolic vulnerability of refractory GISTs is desirable. Methods:. A total o...

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Bibliographic Details
Main Authors: Ying-Chieh Lai, MD, Gigin Lin, MD, PhD, Kung-Chu Ho, MD, Kuan-Ying Lu, MS, Cheng-Kun Tsai, PhD, Cheng-Yu Hung, PhD, Ta-Sen Yeh, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer Health 2022-12-01
Series:Annals of Surgery Open
Online Access:http://journals.lww.com/10.1097/AS9.0000000000000224