Aspartate and Acetate Fuel Gastrointestinal Stromal Tumors Beyond the Warburg Effect
Background:. Metabolic reprogramming is closely linked to the tumorigenesis and drug resistance of gastrointestinal stromal tumors (GISTs). Mapping the metabolic orbit of GISTs is a prerequisite if intervention against the metabolic vulnerability of refractory GISTs is desirable. Methods:. A total o...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Health
2022-12-01
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Series: | Annals of Surgery Open |
Online Access: | http://journals.lww.com/10.1097/AS9.0000000000000224 |