Synergistic Antitumor Potency of a Self-Assembling Cyclodextrin Nanoplex for the Co-Delivery of 5-Fluorouracil and Interleukin-2 in the Treatment of Colorectal Cancer

Synergistic Antitumor Potency of a Self-Assembling Cyclodextrin Nanoplex for the Co-Delivery of 5-Fluorouracil and Interleukin-2 in the Treatment of Colorectal Cancer

Chemotherapy is the most used method after surgery in the treatment of colon cancer. Cancer cells escape the recognition mechanism of immune system cells to survive and develop chemoresistance. Therefore, the use of immunotherapy in combination with chemotherapy can increase the effectiveness of the...

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Bibliographic Details
Main Authors: Safiye Akkın, Gamze Varan, Anıl Işık, Sibel Gökşen, Elif Karakoç, Milo Malanga, Güneş Esendağlı, Petek Korkusuz, Erem Bilensoy
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
chemoimmunotherapy
5-Fluorouracil
Interleukin-2
cyclodextrin polymer
nanoplex
3D cell culture
Online Access:https://www.mdpi.com/1999-4923/15/2/314

Internet

https://www.mdpi.com/1999-4923/15/2/314

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