Lung function measurements in rodents in safety pharmacology studies
The ICH guideline S7A requires safety pharmacology tests including measurements of pulmonary function. In the first step – as part of the core battery - lung function tests in conscious animals are requested. If potential adverse effects raise concern for human safety, these should be explored in a...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-08-01
|
| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00156/full |