Docosahexaenoic acid impairs the maturation of very low density lipoproteins in rat hepatic cells

One mechanism of the lipid-lowering effects of the fish oil n-3 fatty acids [e.g., docosahexaenoic acid (DHA)] in cell and animal models is induced hepatic apolipoprotein B100 (apoB) presecretory degradation. This degradation occurs post-endoplasmic reticulum, but whether DHA induces it before or af...

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Bibliographic Details
Main Authors: Vatsala Maitin, Ursula Andreo, Liang Guo, Edward A. Fisher
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520317430