Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis

Abstract In the adult mammalian brain, neural stem cells (NSCs) located in highly restricted niches sustain the generation of new neurons that integrate into existing circuits. A reduction in adult neurogenesis is linked to ageing and neurodegeneration, whereas dysregulation of proliferation and sur...

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Bibliographic Details
Main Authors: Ana del Puerto, Coral Lopez-Fonseca, Ana Simón-García, Beatriz Martí-Prado, Ana L. Barrios-Muñoz, Julia Pose-Utrilla, Celia López-Menéndez, Berta Alcover-Sanchez, Fabrizia Cesca, Giampietro Schiavo, Miguel R. Campanero, Isabel Fariñas, Teresa Iglesias, Eva Porlan
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05995-7