Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis
Abstract In the adult mammalian brain, neural stem cells (NSCs) located in highly restricted niches sustain the generation of new neurons that integrate into existing circuits. A reduction in adult neurogenesis is linked to ageing and neurodegeneration, whereas dysregulation of proliferation and sur...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-08-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05995-7 |