Structural variants shape the genomic landscape and clinical outcome of multiple myeloma

Structural variants shape the genomic landscape and clinical outcome of multiple myeloma

Abstract Deciphering genomic architecture is key to identifying novel disease drivers and understanding the mechanisms underlying myeloma initiation and progression. In this work, using the CoMMpass dataset, we show that structural variants (SV) occur in a nonrandom fashion throughout the genome wit...

Full description

Bibliographic Details
Main Authors: Cody Ashby, Eileen M. Boyle, Michael A. Bauer, Aneta Mikulasova, Christopher P. Wardell, Louis Williams, Ariel Siegel, Patrick Blaney, Marc Braunstein, David Kaminetsky, Jonathan Keats, Francesco Maura, Ola Landgren, Brian A. Walker, Faith E. Davies, Gareth J. Morgan
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-022-00673-x

Internet

https://doi.org/10.1038/s41408-022-00673-x

Similar Items