Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the Patients of Type–II Diabetes Mellitus

BACKGROUND: Diabetes mellitus and dyslipidemia with their complications disclose unscrupulous impact on human health, and increase the rate of mortality all over the world. The allopathic medicine is being used and consumed all over the world for the treatment of hazardous disease and their complica...

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Main Authors: Ali Raza Memon, Allah Bux Ghanghro, Imran Ali Shaikh, Nasreen Qazi, Irshad Hussain Ghanghro, Umair Shaikh
Format: Article
Language:English
Published: Liaquat University of Medical and Health Sciences 2018-06-01
Series:JLUMHS
Subjects:
Online Access:https://www.lumhs.edu.pk/jlumhs/Vol17No02/pdfs/08.pdf
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author Ali Raza Memon
Allah Bux Ghanghro
Imran Ali Shaikh
Nasreen Qazi
Irshad Hussain Ghanghro
Umair Shaikh
author_facet Ali Raza Memon
Allah Bux Ghanghro
Imran Ali Shaikh
Nasreen Qazi
Irshad Hussain Ghanghro
Umair Shaikh
author_sort Ali Raza Memon
collection DOAJ
description BACKGROUND: Diabetes mellitus and dyslipidemia with their complications disclose unscrupulous impact on human health, and increase the rate of mortality all over the world. The allopathic medicine is being used and consumed all over the world for the treatment of hazardous disease and their complications. Nowadays hypothesis has raised that natural production like olive oil and garlic etc having potential benefits to control glycemic control, blood cholesterol, triglycerides, lipoproteins (Low density lipoprotein & High density ipoprotein). AIMS & OBJECTIVE: To evaluate the effects of natural remedies (combination of olive oil & garlic) on serum cholesterol and serum triglyceride(TAG’s) levels with comparison to conventional allopathic (statin) therapy. METHODOLOGY: This Randomized Control Trial (RCT) study conducted at Institute of Biochemistry Sindh University Jamshoro with collaboration of diabetic clinic medical wards LUMHS Jamshoro. Total 160 patients recruited and divided into two groups as control and case study group. Anti diabetic and statin drugs were given to each group with same dose and balanced diet, formulated capsules containing 1.1 ml of olive oil & 500mgs of garlic powder were given only patients of case study group for 3 months. Biochemical analysis of serum cholesterol & serum TAG’s was done at zero level, level – I & level – II by enzymatic caloric method on Cobas auto analyzer. RESULTS: The study presented that serum cholesterol level & serum TAG’s levels were statistically normalized in case study group as compared to control group. CONCLUSION: The natural remedies (Phyto therapy) have an important role in the treatment of dyslipidemia in type – II diabetic patients, so Phyto therapy can also takes part in the prevention of complications due to dyslipidemia in diabetic population.
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spelling doaj.art-bfe2a5b161f04637afa6b9cb748b2e7b2023-05-30T09:54:06ZengLiaquat University of Medical and Health SciencesJLUMHS1729-03412309-86272018-06-01170210110510.22442/jlumhs.181720559Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the Patients of Type–II Diabetes MellitusAli Raza Memon 0Allah Bux Ghanghro1Imran Ali Shaikh2Nasreen Qazi3Irshad Hussain Ghanghro4Umair Shaikh5Liaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanUniversity of Sindh, Jamshoro, Sindh-PakistanLiaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanLiaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanLiaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanLiaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-PakistanBACKGROUND: Diabetes mellitus and dyslipidemia with their complications disclose unscrupulous impact on human health, and increase the rate of mortality all over the world. The allopathic medicine is being used and consumed all over the world for the treatment of hazardous disease and their complications. Nowadays hypothesis has raised that natural production like olive oil and garlic etc having potential benefits to control glycemic control, blood cholesterol, triglycerides, lipoproteins (Low density lipoprotein & High density ipoprotein). AIMS & OBJECTIVE: To evaluate the effects of natural remedies (combination of olive oil & garlic) on serum cholesterol and serum triglyceride(TAG’s) levels with comparison to conventional allopathic (statin) therapy. METHODOLOGY: This Randomized Control Trial (RCT) study conducted at Institute of Biochemistry Sindh University Jamshoro with collaboration of diabetic clinic medical wards LUMHS Jamshoro. Total 160 patients recruited and divided into two groups as control and case study group. Anti diabetic and statin drugs were given to each group with same dose and balanced diet, formulated capsules containing 1.1 ml of olive oil & 500mgs of garlic powder were given only patients of case study group for 3 months. Biochemical analysis of serum cholesterol & serum TAG’s was done at zero level, level – I & level – II by enzymatic caloric method on Cobas auto analyzer. RESULTS: The study presented that serum cholesterol level & serum TAG’s levels were statistically normalized in case study group as compared to control group. CONCLUSION: The natural remedies (Phyto therapy) have an important role in the treatment of dyslipidemia in type – II diabetic patients, so Phyto therapy can also takes part in the prevention of complications due to dyslipidemia in diabetic population.https://www.lumhs.edu.pk/jlumhs/Vol17No02/pdfs/08.pdfdiabetes mellitushypercholesterolemiatriglyceridesolive oilgarlicstatin drugs.
spellingShingle Ali Raza Memon
Allah Bux Ghanghro
Imran Ali Shaikh
Nasreen Qazi
Irshad Hussain Ghanghro
Umair Shaikh
Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the Patients of Type–II Diabetes Mellitus
JLUMHS
diabetes mellitus
hypercholesterolemia
triglycerides
olive oil
garlic
statin drugs.
title Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the Patients of Type–II Diabetes Mellitus
title_full Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the Patients of Type–II Diabetes Mellitus
title_fullStr Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the Patients of Type–II Diabetes Mellitus
title_full_unstemmed Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the Patients of Type–II Diabetes Mellitus
title_short Effects of Olive Oil and Garlic on Serum Cholesterol and Triglycerides Levels in the Patients of Type–II Diabetes Mellitus
title_sort effects of olive oil and garlic on serum cholesterol and triglycerides levels in the patients of type ii diabetes mellitus
topic diabetes mellitus
hypercholesterolemia
triglycerides
olive oil
garlic
statin drugs.
url https://www.lumhs.edu.pk/jlumhs/Vol17No02/pdfs/08.pdf
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