Denervated mouse CA1 pyramidal neurons express homeostatic synaptic plasticity following entorhinal cortex lesion

Denervated mouse CA1 pyramidal neurons express homeostatic synaptic plasticity following entorhinal cortex lesion

Structural, functional, and molecular reorganization of denervated neural networks is often observed in neurological conditions. The loss of input is accompanied by homeostatic synaptic adaptations, which can affect the reorganization process. A major challenge of denervation-induced homeostatic pla...

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Bibliographic Details
Main Authors: Maximilian Lenz, Amelie Eichler, Pia Kruse, Phyllis Stöhr, Dimitrios Kleidonas, Christos Galanis, Han Lu, Andreas Vlachos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
entorhinal cortex lesion
Schaffer collateral lesion
transcriptome analysis
microglia
RNA oxidation
synaptic plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1148219/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1148219/full

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