Deaminase-Independent Mode of Antiretroviral Action in Human and Mouse APOBEC3 Proteins
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 (APOBEC3) proteins (APOBEC3s) are deaminases that convert cytosines to uracils predominantly on a single-stranded DNA, and function as intrinsic restriction factors in the innate immune system to suppress replication of viruses (incl...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Microorganisms |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-2607/8/12/1976 |