<italic toggle="yes">In Vivo</italic> Genome and Methylome Adaptation of <italic toggle="yes">cag</italic>-Negative <named-content content-type="genus-species">Helicobacter pylori</named-content> during Experimental Human Infection

<italic toggle="yes">In Vivo</italic> Genome and Methylome Adaptation of <italic toggle="yes">cag</italic>-Negative <named-content content-type="genus-species">Helicobacter pylori</named-content> during Experimental Human Infection

ABSTRACT Multiple studies have demonstrated rapid bacterial genome evolution during chronic infection with Helicobacter pylori. In contrast, little was known about genetic changes during the first stages of infection, when selective pressure is likely to be highest. Using single-molecule, real-time...

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Bibliographic Details
Main Authors: Iratxe Estibariz, Florent Ailloud, Sabrina Woltemate, Boyke Bunk, Cathrin Spröer, Jörg Overmann, Toni Aebischer, Thomas F. Meyer, Christine Josenhans, Sebastian Suerbaum
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mBio
Subjects:
DNA methylation
Helicobacter pylori
adaptive mutations
genome analysis
SMRT sequencing
PacBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01803-20

Internet

https://journals.asm.org/doi/10.1128/mBio.01803-20

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