Mathematical model of the cell signaling pathway based on the extended Boolean network model with a stochastic process

Abstract Background In cell signaling pathways, proteins interact with each other to determine cell fate in response to either cell-extrinsic (micro-environmental) or intrinsic cues. One of the well-studied pathways, the mitogen-activated protein kinase (MAPK) signaling pathway, regulates cell proce...

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Bibliographic Details
Main Authors: Minsoo Kim, Eunjung Kim
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-05077-z