Identification of ATF3 as a novel protective signature of quiescent colorectal tumor cells

Abstract Colorectal cancer (CRC) is the third most common cancer and the second leading cause of death in the world. In most cases, drug resistance and tumor recurrence are ultimately inevitable. One obstacle is the presence of chemotherapy-insensitive quiescent cancer cells (QCCs). Identification o...

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Bibliographic Details
Main Authors: Xi Lu, Lei Zhong, Emma Lindell, Margus Veanes, Jing Guo, Miao Zhao, Maede Salehi, Fredrik J. Swartling, Xingqi Chen, Tobias Sjöblom, Xiaonan Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06204-1