Cellular assays identify barriers impeding iron-sulfur enzyme activity in a non-native prokaryotic host

Cellular assays identify barriers impeding iron-sulfur enzyme activity in a non-native prokaryotic host

Iron-sulfur (Fe-S) clusters are ancient and ubiquitous protein cofactors and play irreplaceable roles in many metabolic and regulatory processes. Fe-S clusters are built and distributed to Fe-S enzymes by dedicated protein networks. The core components of these networks are widely conserved and high...

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Bibliographic Details
Main Authors: Francesca D'Angelo, Elena Fernández-Fueyo, Pierre Simon Garcia, Helena Shomar, Martin Pelosse, Rita Rebelo Manuel, Ferhat Büke, Siyi Liu, Niels van den Broek, Nicolas Duraffourg, Carol de Ram, Martin Pabst, Emmanuelle Bouveret, Simonetta Gribaldo, Béatrice Py, Sandrine Ollagnier de Choudens, Frédéric Barras, Gregory Bokinsky
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
iron-sulfur enzyme
horizontal gene transfer
microbial engineering
electron transfer protein
Online Access:https://elifesciences.org/articles/70936

Internet

https://elifesciences.org/articles/70936

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