Sex-Dependent Modulation of Acute Stress Reactivity After Early Life Stress in Mice: Relevance of Mineralocorticoid Receptor Expression

Sex-Dependent Modulation of Acute Stress Reactivity After Early Life Stress in Mice: Relevance of Mineralocorticoid Receptor Expression

Early life stress (ELS) is considered a major risk factor for developing psychopathology. Increasing evidence points towards sex-dependent dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis as a contributing mechanism. Additionally, clinical studies suggest that the mineralocorticoid rec...

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Bibliographic Details
Main Authors: Valeria Bonapersona, Ruth Damsteegt, Mirjam L. Adams, Lisa T. C. M. van Weert, Onno C. Meijer, Marian Joëls, Ratna Angela Sarabdjitsingh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
mineralocorticoid receptor
early life stress (ELS)
HPA axis
neuroendocrine
behavior
corticosterone
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2019.00181/full

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https://www.frontiersin.org/article/10.3389/fnbeh.2019.00181/full

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