Design of Inhibitors That Target the Menin–Mixed-Lineage Leukemia Interaction

The prognosis of mixed-lineage leukemia (MLL) has remained a significant health concern, especially for infants. The minimal treatments available for this aggressive type of leukemia has been an ongoing problem. Chromosomal translocations of the KMT2A gene are known as MLL, which expresses MLL fusio...

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Bibliographic Details
Main Authors: Moses N. Arthur, Kristeen Bebla, Emmanuel Broni, Carolyn Ashley, Miriam Velazquez, Xianin Hua, Ravi Radhakrishnan, Samuel K. Kwofie, Whelton A. Miller
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Computation
Subjects:
Online Access:https://www.mdpi.com/2079-3197/12/1/3