Selenium-Containing Protein From Selenium-Enriched Spirulina platensis Attenuates Cisplatin-Induced Apoptosis in MC3T3-E1 Mouse Preosteoblast by Inhibiting Mitochondrial Dysfunction and ROS-Mediated Oxidative Damage

Selenium-Containing Protein From Selenium-Enriched Spirulina platensis Attenuates Cisplatin-Induced Apoptosis in MC3T3-E1 Mouse Preosteoblast by Inhibiting Mitochondrial Dysfunction and ROS-Mediated Oxidative Damage

Accumulated evidences have verified that cancer chemotherapy may increase the risk of osteoporosis and severely affected the life quality. Osteoclasts hyperactivation was commonly accepted as the major pathogenesis of osteoporosis. However, the role of osteoblasts dysfunction in osteoporosis was lit...

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Bibliographic Details
Main Authors: Jing-yi Sun, Ya-jun Hou, Xiao-yan Fu, Xiao-ting Fu, Jin-kui Ma, Ming-feng Yang, Bao-liang Sun, Cun-dong Fan, Jinrok Oh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Physiology
Subjects:
osteoporosis
osteoblasts dysfunction
selenium-containing protein
cancer chemotherapy
mitochondrial dysfunction
oxidative damage
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01907/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01907/full

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