DABCO-Customized Nanoemulsions: Characterization, Cell Viability and Genotoxicity in Retinal Pigmented Epithelium and Microglia Cells

DABCO-Customized Nanoemulsions: Characterization, Cell Viability and Genotoxicity in Retinal Pigmented Epithelium and Microglia Cells

Quaternary derivatives of 1,4-diazabicyclo[2.2.2]octane (DABCO) and of quinuclidine surfactants were used to develop oil-in-water nanoemulsions with the purpose of selecting the best long-term stable nanoemulsion for the ocular administration of triamcinolone acetonide (TA). The combination of the b...

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Bibliographic Details
Main Authors: Ana R. Fernandes, Tiago dos Santos, Pedro L. Granja, Elena Sanchez-Lopez, Antonello Santini, Maria L. Garcia, Amelia M. Silva, Eliana B. Souto
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
cationic nanoemulsions
DABCO surfactants
quinuclidine surfactants
ocular administration
triamcinolone acetonide
age-related macular degeneration
Online Access:https://www.mdpi.com/1999-4923/13/10/1652

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https://www.mdpi.com/1999-4923/13/10/1652

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