RNA-Seq reveals changes in human placental metabolism, transport and endocrinology across the first–second trimester transition

RNA-Seq reveals changes in human placental metabolism, transport and endocrinology across the first–second trimester transition

The human placenta is exposed to major environmental changes towards the end of the first trimester associated with full onset of the maternal arterial placental circulation. Changes include a switch from histotrophic to hemotrophic nutrition, and a threefold rise in the intraplacental oxygen concen...

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Bibliographic Details
Main Authors: Malwina Prater, Russell S. Hamilton, Hong Wa Yung, Andrew M. Sharkey, Paul Robson, N. Erlyani Abd Hamid, Eric Jauniaux, D. Stephen Charnock-Jones, Graham J. Burton, Tereza Cindrova-Davies
Format: Article
Language:English
Published: The Company of Biologists 2021-06-01
Series:Biology Open
Subjects:
early placenta
metabolism
transcriptome
human pregnancy
methylation
Online Access:http://bio.biologists.org/content/10/6/bio058222

Internet

http://bio.biologists.org/content/10/6/bio058222

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