Encapsulation of Clofazimine by Cyclodextran: Preparation, Characterization, and In Vitro Release Properties

Encapsulation of Clofazimine by Cyclodextran: Preparation, Characterization, and In Vitro Release Properties

This study aimed to evaluate and compare the efficacy of cyclodextrans (CIs) and cyclodextrins (CDs) in improving the water solubility of a poorly water-soluble drug, clofazimine (CFZ). Among the evaluated CIs and CDs, CI-9 exhibited the highest percentage of drug inclusion and the highest solubilit...

Full description

Bibliographic Details
Main Authors: Seong-Jin Hong, Young-Min Kim
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
clofazimine
cyclodextran
cyclodextrin
inclusion complex
drug release properties
Online Access:https://www.mdpi.com/1422-0067/24/10/8808

Internet

https://www.mdpi.com/1422-0067/24/10/8808

Similar Items