Lung-Derived Microscaffolds Facilitate Diabetes Reversal after Mouse and Human Intraperitoneal Islet Transplantation.

Lung-Derived Microscaffolds Facilitate Diabetes Reversal after Mouse and Human Intraperitoneal Islet Transplantation.

There is a need to develop three-dimensional structures that mimic the natural islet tissue microenvironment. Endocrine micro-pancreata (EMPs) made up of acellular organ-derived micro-scaffolds seeded with human islets have been shown to express high levels of key beta-cell specific genes and secret...

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Bibliographic Details
Main Authors: Nasser Abualhassan, Lena Sapozhnikov, Rena L Pawlick, Meygal Kahana, Andrew R Pepper, Antonio Bruni, Boris Gala-Lopez, Tatsuya Kin, Eduardo Mitrani, A M James Shapiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4881949?pdf=render

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http://europepmc.org/articles/PMC4881949?pdf=render

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