Analysis of large deletion mutations induced by abasic site analog in human cells
Abstract Background Abasic sites are formed spontaneously and by nucleobase chemical modifications and base excision repair. A chemically stable abasic site analog was site-specifically introduced into replicable plasmid DNAs, which were transfected into human U2OS cells. The amplified DNAs were rec...
প্রধান লেখক: | , , , |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
BMC
2018-10-01
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মালা: | Genes and Environment |
বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | http://link.springer.com/article/10.1186/s41021-018-0110-7 |