Mesenchymal stromal cells induced regulatory B cells are enriched in extracellular matrix genes and IL-10 independent modulators

Mesenchymal stromal cells induced regulatory B cells are enriched in extracellular matrix genes and IL-10 independent modulators

Regulatory B cells (Breg) are essential players in tolerance and immune homeostasis. However, lack of specific Breg markers limit their potential in clinical settings. Mesenchymal stromal cells (MSC) modulate B cell responses and are described to induce Breg in vitro. The aim of this work was to cha...

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Bibliographic Details
Main Authors: Sergio G. Garcia, Noelia Sandoval-Hellín, Marta Clos-Sansalvador, Laura Carreras-Planella, Miriam Morón-Font, Dolores Guerrero, Francesc E. Borràs, Marcella Franquesa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
B cell
immunomodulation
mesenchymal stromal cell
regulatory B cell
IL-10
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.957797/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.957797/full

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