Protective Effect of Hawthorn Fruit Extract against High Fructose-Induced Oxidative Stress and Endoplasmic Reticulum Stress in Pancreatic β-Cells

Protective Effect of Hawthorn Fruit Extract against High Fructose-Induced Oxidative Stress and Endoplasmic Reticulum Stress in Pancreatic β-Cells

Hyperglycemia has deleterious effects on pancreatic β-cells, causing dysfunction and insulin resistance that lead to diabetes mellitus (DM). The possible causes of injury can be caused by glucose- or fructose-induced oxidative and endoplasmic reticulum (ER) stress. Hawthorn (<i>Crataegus pinna...

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Bibliographic Details
Main Authors: Hsiu-Man Lien, Hsin-Tang Lin, Shiau-Huei Huang, Yìng-Ru Chen, Chao-Lu Huang, Chia-Chang Chen, Charng-Cherng Chyau
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Foods
Subjects:
hawthorn fruit
<i>Crataegus pinnatifida</i>
polyphenol-enriched extract
pancreatic β-cell
hyperglycemia
endoplasmic reticulum (ER) stress
Online Access:https://www.mdpi.com/2304-8158/12/6/1130

Internet

https://www.mdpi.com/2304-8158/12/6/1130

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