Widespread evolutionary crosstalk among protein domains in the context of multi-domain proteins.

Domains are distinct units within proteins that typically can fold independently into recognizable three-dimensional structures to facilitate their functions. The structural and functional independence of protein domains is reflected by their apparent modularity in the context of multi-domain protei...

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Bibliographic Details
Main Authors: David Jakubec, Miroslav Kratochvíl, Jiří Vymĕtal, Jiří Vondrášek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6118372?pdf=render