Homologous Recombination Repair in Biliary Tract Cancers: A Prime Target for PARP Inhibition?

Biliary tract cancers (BTCs) are a heterogeneous group of malignancies that make up ~7% of all gastrointestinal tumors. It is notably aggressive and difficult to treat; in fact, >70% of patients with BTC are diagnosed at an advanced, unresectable stage and are not amenable to curative therapy. Fo...

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Bibliographic Details
Main Authors: Chao Yin, Monika Kulasekaran, Tina Roy, Brennan Decker, Sonja Alexander, Mathew Margolis, Reena C. Jha, Gary M. Kupfer, Aiwu R. He
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/10/2561