Tolerance induction through non-avoidance to prevent persistent food allergy (TINA) in children and adults with peanut or tree nut allergy: rationale, study design and methods of a randomized controlled trial and observational cohort study

Tolerance induction through non-avoidance to prevent persistent food allergy (TINA) in children and adults with peanut or tree nut allergy: rationale, study design and methods of a randomized controlled trial and observational cohort study

Abstract Background Peanuts (PN) and tree nuts (TN) are among the most frequent elicitors of food allergy and can lead to life-threatening reactions. The current advice for allergic patients is to strictly avoid the offending food independently of their individual threshold level, whereas sensitized...

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Bibliographic Details
Main Authors: Valérie Trendelenburg, Sabine Dölle-Bierke, Nathalie Unterleider, Aikaterina Alexiou, Birgit Kalb, Lara Meixner, Stephanie Heller, Susanne Lau, Young- Ae Lee, Florent Fauchère, Julian Braun, Magda Babina, Sabine Altrichter, Till Birkner, Stephanie Roll, Josefine Dobbertin-Welsch, Margitta Worm, Kirsten Beyer
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Trials
Subjects:
Protocol
Randomized controlled trial
Peanut allergy
Tree nut allergy
Elimination diet
Higher threshold
Online Access:https://doi.org/10.1186/s13063-022-06149-4

Internet

https://doi.org/10.1186/s13063-022-06149-4

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