Regulation of Microglial Functions by Purinergic Mechanisms in the Healthy and Diseased CNS

Microglial cells, the resident macrophages of the central nervous system (CNS), exist in a process-bearing, ramified/surveying phenotype under resting conditions. Upon activation by cell-damaging factors, they get transformed into an amoeboid phenotype releasing various cell products including pro-i...

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Bibliographic Details
Main Authors: Peter Illes, Patrizia Rubini, Henning Ulrich, Yafei Zhao, Yong Tang
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/5/1108