Fc or not Fc; that is the question: Antibody Fc-receptor interactions are key to universal influenza vaccine design

A universal vaccine that provides long-lasting protection from both epidemic and pandemic influenza viruses remains the “holy grail” of influenza vaccine research. Though virus neutralization assays are the current benchmark of measuring vaccine effectiveness, it is clear that Fc-receptor functions...

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Bibliographic Details
Main Authors: Sinthujan Jegaskanda, Hillary A. Vanderven, Adam K. Wheatley, Stephen J. Kent
Format: Article
Language:English
Published: Taylor & Francis Group 2017-06-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2017.1290018