HLA molecular mismatches and induced donor-specific tolerance in combined living donor kidney and hematopoietic stem cell transplantation

HLA molecular mismatches and induced donor-specific tolerance in combined living donor kidney and hematopoietic stem cell transplantation

IntroductionWe investigated the potential role of HLA molecular mismatches (MM) in achieving stable chimerism, allowing for donor-specific tolerance in patients undergoing combined living donor kidney and hematopoietic stem cell transplantation (HSCT).MethodsAll patients with available DNA samples (...

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Bibliographic Details
Main Authors: Aleksandar Senev, Anat R. Tambur, Vasilis Kosmoliaptsis, Hannah Charlotte Copley, Cynthia García-Sánchez, Crystal Usenko, Suzanne T. Ildstad, Joseph R. Leventhal
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
HLA
kidney transplantation
stem cell transplantation
tolerance
HLA epitope analysis
HLA molecular mismatches
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1377535/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1377535/full

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