Interaction of Purinergic P2X4 and P2X7 Receptor Subunits

Interaction of Purinergic P2X4 and P2X7 Receptor Subunits

P2X4 and P2X7 are members of the P2X receptor family, comprising seven isoforms (P2X1–P2X7) that form homo- and heterotrimeric non-specific cation channels gated by extracellular ATP. P2X4 and P2X7 are widely coexpressed, particularly in secretory epithelial cells and immune and inflammatory cells,...

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Bibliografski detalji
Glavni autori: Markus Schneider, Kirsten Prudic, Anja Pippel, Manuela Klapperstück, Ursula Braam, Christa E. Müller, Günther Schmalzing, Fritz Markwardt
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2017-11-01
Serija:Frontiers in Pharmacology
Teme:
P2X7
P2X4
voltage clamp
fluorescence
FRET
interaction
Online pristup:http://journal.frontiersin.org/article/10.3389/fphar.2017.00860/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00860/full

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