An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence

An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence

Abstract High-grade gliomas are primary brain tumors that are incredibly refractory long-term to surgery and chemoradiation, with no proven durable salvage therapies for patients that have failed conventional treatments. Post-treatment, the latent glioma and its microenvironment are characterized by...

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Bibliographic Details
Main Authors: Cecile Riviere-Cazaux, Lucas P. Carlstrom, Bryan J. Neth, Ian E. Olson, Karishma Rajani, Masum Rahman, Samar Ikram, Moustafa A. Mansour, Bipasha Mukherjee, Arthur E. Warrington, Susan C. Short, Thomas von Zglinicki, Desmond A. Brown, Sandeep Burma, Tamar Tchkonia, Marissa J. Schafer, Darren J. Baker, Sani H. Kizilbash, James L. Kirkland, Terry C. Burns
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00476-8

Internet

https://doi.org/10.1038/s41698-023-00476-8

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