Study of the safety and immunogenicity of VLP-based vaccine for the prevention of rotavirus infection in neonatal minipig model

Study of the safety and immunogenicity of VLP-based vaccine for the prevention of rotavirus infection in neonatal minipig model

Introduction. In Russia, almost half of the cases of acute intestinal infections of established etiology in 2022 are due to rotavirus infection (RVI). There is no specific treatment for rotavirus gastroenteritis. There is a need to develop modern, effective and safe vaccines to combat rotavirus infe...

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Bibliographic Details
Main Authors: Ludmila V. Kostina, Ilya E. Filatov, Olesya V. Eliseeva, Oleg E. Latyshev, Yana Yu. Chernoryzh, Kirill I. Yurlov, Ekaterina I. Lesnova, Kizkhalum M. Khametova, Stanislav A. Cherepushkin, Tatyana E. Savochkina, Valery V. Tsibezov, Kirill L. Kryshen, Liubov I. Alekseeva, Olga N. Zaykova, Tatyana V. Grebennikova
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2023-11-01
Series:Вопросы вирусологии
Subjects:
human rotavirus a
vaccine
virus-like particles
preclinical study
minipigs
Online Access:https://virusjour.crie.ru/jour/article/viewFile/16152/814

Internet

https://virusjour.crie.ru/jour/article/viewFile/16152/814

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