Physical constraints in polymer modeling of chromatin associations with the nuclear periphery at kilobase scale

Interactions of chromatin with the nuclear lamina imposes a radial genome distribution important for nuclear functions. How physical properties of chromatin affect these interactions is unclear. We used polymer simulations to model how physical parameters of chromatin affect its interaction with the...

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Bibliographic Details
Main Authors: Annaël Brunet, Nicolas Destainville, Philippe Collas
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Nucleus
Subjects:
Online Access:http://dx.doi.org/10.1080/19491034.2020.1868105