Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients

Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients

Abstract Background The HER2-HER3 heterodimer significantly decreases survival in breast cancer patients. However, the prognostic value of HER2-HER3 overexpression remains unknown in gastric cancer (GC). Methods The expression levels of HER2, HER3, Akt, p-Akt, mTOR and p-mTOR were examined in specim...

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Bibliographic Details
Main Authors: Guo-dong Cao, Ke Chen, Bo Chen, Mao-ming Xiong
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cancer
Subjects:
HER2
HER3
mTOR
Prognosis
Gastric cancer
Online Access:http://link.springer.com/article/10.1186/s12885-017-3851-y

Internet

http://link.springer.com/article/10.1186/s12885-017-3851-y

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