Supplementation with high-GABA-producing Lactobacillus plantarum L5 ameliorates essential tremor triggered by decreased gut bacteria-derived GABA

Supplementation with high-GABA-producing Lactobacillus plantarum L5 ameliorates essential tremor triggered by decreased gut bacteria-derived GABA

Abstract Background The γ-aminobutyric acid (GABA) hypothesis posits a role of GABA deficiency in the central nervous system in the pathogenesis and progression of essential tremor (ET). However, the specific causative factor for GABA deficiency is not clear. The gut microbiota in mammals has recent...

Full description

Bibliographic Details
Main Authors: Hao-Jie Zhong, Si-Qi Wang, Ruo-Xin Zhang, Yu-Pei Zhuang, Longyan Li, Shuo-Zhao Yi, Ying Li, Lei Wu, Yu Ding, Jumei Zhang, Xinqiang Xie, Xing-Xiang He, Qingping Wu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Translational Neurodegeneration
Subjects:
Cerebellum
Essential tremor
Gamma-aminobutyric acid
Gut microbiota
Lactobacillus plantarum
Online Access:https://doi.org/10.1186/s40035-023-00391-9

Internet

https://doi.org/10.1186/s40035-023-00391-9

Similar Items