Alpha1A- and Beta3-Adrenoceptors Interplay in Adipose Multipotent Mesenchymal Stromal Cells: A Novel Mechanism of Obesity-Driven Hypertension

Alpha1A- and Beta3-Adrenoceptors Interplay in Adipose Multipotent Mesenchymal Stromal Cells: A Novel Mechanism of Obesity-Driven Hypertension

Hypertension is a major risk factor for cardiovascular diseases, such as strokes and myocardial infarctions. Nearly 70% of hypertension onsets in adults can be attributed to obesity, primarily due to sympathetic overdrive and the dysregulated renin-angiotensin system. Sympathetic overdrive increases...

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Bibliographic Details
Main Authors: Vadim Chechekhin, Anastasia Ivanova, Konstantin Kulebyakin, Veronika Sysoeva, Daria Naida, Mikhail Arbatsky, Nataliya Basalova, Maxim Karagyaur, Mariya Skryabina, Anastasia Efimenko, Olga Grigorieva, Natalia Kalinina, Vsevolod Tkachuk, Pyotr Tyurin-Kuzmin
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
obesity
hypertension
sympathetic nervous system
MSCs
adrenergic receptors
contractile phenotype
Online Access:https://www.mdpi.com/2073-4409/12/4/585

Internet

https://www.mdpi.com/2073-4409/12/4/585

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