The Secretome Derived From Mesenchymal Stromal Cells Cultured in a Xeno-Free Medium Promotes Human Cartilage Recovery in vitro

The Secretome Derived From Mesenchymal Stromal Cells Cultured in a Xeno-Free Medium Promotes Human Cartilage Recovery in vitro

Osteoarthritis (OA) is a disabling joint disorder causing articular cartilage degeneration. Currently, the treatments are mainly aimed to pain and symptoms relief, rather than disease amelioration. Human bone marrow stromal cells (hBMSCs) have emerged as a promising paracrine mechanism-based tool fo...

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Bibliographic Details
Main Authors: Maria Elisabetta Federica Palamà, Georgina Margaret Shaw, Simonetta Carluccio, Daniele Reverberi, Laura Sercia, Luana Persano, Dario Pisignano, Katia Cortese, Francis Peter Barry, Josephine Mary Murphy, Chiara Gentili
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mesenchymal stromal cells
secretome
extracellular vesicles
xeno-free medium
inflammation
osteoarthritis
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00090/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00090/full

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