Genetic and antiretroviral drug resistance mutations analysis of reverse transcriptase and protease gene from Pakistani people living with HIV-1.

<h4>Background</h4>Antiretroviral therapy (ART) effectiveness is compromised by the emergence of HIV drug resistance mutations (DRM) and can lead to the failure of ART. Apart from intrinsic viral factors, non-compliance with drugs and/or the use of sub-optimum therapy can lead to the eme...

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Main Authors: Dilsha Siddiqui, Uzma Badar, Mahnoor Javaid, Nida Farooqui, Sharaf Ali Shah, Ayesha Iftikhar, Faisal Sultan, Fatima Mir, Sofia Furqan, Syed Faisal Mahmood, Syed Hani Abidi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0290425