The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation

A dynamic, properly organised actin cytoskeleton is critical for the production and haemostatic function of platelets. The Wiskott Aldrich Syndrome protein (WASp) and Actin-Related Proteins 2 & 3 Complex (Arp2/3 complex) are critical mediators of actin polymerisation and organisation in many cel...

Full description

Bibliographic Details
Main Authors: Steven G. Thomas, Natalie S. Poulter, Danai Bem, Brenda Finney, Laura M. Machesky, Stephen P. Watson
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2016.1235688