Standard Selection Treatments with Sulfadiazine Limit Plasmodium yoelii Host-to-Vector Transmission
ABSTRACT Some antimalarial drugs that have lost clinical usefulness have been repurposed for experimental applications. One example is sulfadiazine, an analog of p-aminobenzoic acid (pABA), which inhibits the parasite’s folate synthesis pathway to block DNA synthesis. Sulfadiazine treatment of mice...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2022-06-01
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| Series: | mSphere |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/msphere.00106-22 |