Evolutionary model for the unequal segregation of high copy plasmids.

Plasmids are extrachromosomal DNA elements of microorganisms encoding beneficial genetic information. They were thought to be equally distributed to daughter cells during cell division. Here we use mathematical modeling to investigate the evolutionary stability of plasmid segregation for high-copy p...

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Bibliographic Details
Main Authors: Karin Münch, Richard Münch, Rebekka Biedendieck, Dieter Jahn, Johannes Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006724