Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series

Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series

Abstract Mycophenolate mofetil has an important role as immunosuppressive agent in solid organ transplant recipients. Exposure to the active mycophenolic acid (MPA) can be monitored using therapeutic drug monitoring. We present three cases in which MPA exposure severely decreased after oral antibiot...

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Bibliographic Details
Main Authors: Mirjam Simoons, Kishan A. T. Naipal, Huib deJong, Caroline M. denHoed, Brenda C. M. deWinter, Midas B. Mulder
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Pharmacology Research & Perspectives
Subjects:
drug interactions
enterohepatic circulation
mycophenolic acid
organ transplantation
patient safety
Online Access:https://doi.org/10.1002/prp2.1103

Internet

https://doi.org/10.1002/prp2.1103

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