Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum

Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum

Abstract Artemisinin combination therapies (ACTs) have led to a significant decrease in Plasmodium falciparum malaria mortality. This progress is now threatened by emerging artemisinin resistance (ART-R) linked originally in SE Asia to polymorphisms in the Kelch propeller protein (K13) and more rece...

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Bibliographic Details
Main Authors: Caroline F. Simmons, Justin Gibbons, Min Zhang, Jenna Oberstaller, Camilla Valente Pires, Debora Casandra, Chengqi Wang, Andreas Seyfang, Thomas D. Otto, Julian C. Rayner, John H. Adams
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-27417-6

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https://doi.org/10.1038/s41598-023-27417-6

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