A novel feedback regulated loop of circRRM2-IGF2BP1-MYC promotes breast cancer metastasis

Abstract Background Metastasis is the leading cause of mortality in patients with breast cancer (BC). Studies demonstrate that circular RNAs (circRNAs) were involved in BC progression, while the molecular mechanisms remain largely unclear. Methods The microArray circRNA profiles were used to explore...

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Bibliographic Details
Main Authors: Ran Hao, Lei Zhang, Yangming Si, Peng Zhang, Yipeng Wang, Bangchao Li, Jie Hu, Yixin Qi
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-02895-w