Discoidin domain receptor 2 activation of p38 mitogen-activated protein kinase as an important pathway for osteonectin-regulating osteoblast mineralization

Abstract Objective The present study aimed to determine the role of the discoidin domain receptor 2 (DDR2) in the osteonectin (ON) regulation of osteoblast mineralization through the activation of p38 mitogen-activated protein kinase (MAPK). Methods Four groups were established: the ON group, the in...

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Bibliographic Details
Main Authors: Yun-Sen Zhu, Jiang-Nan Zhang, Ting-Ting Mo, Chang Jiang, Ru-Chao Ma, Liang Chen
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-021-02860-1