Metabolic Regulation of Hematopoietic Stem Cells

Cellular metabolism is a key regulator of hematopoietic stem cell (HSC) maintenance. HSCs rely on anaerobic glycolysis for energy production to minimize the production of reactive oxygen species and shift toward mitochondrial oxidative phosphorylation upon differentiation. However, increasing eviden...

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Bibliographic Details
Main Authors: Claudia Morganti, Nina Cabezas-Wallscheid, Keisuke Ito
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000740